ЛЕНВАТИНИБ В ЛЕЧЕНИИ РАДИОЙОДРЕФРАКТЕРНОГО ВЫСОКОДИФФЕРЕНЦИРОВАННОГО РАКА ЩИТОВИДНОЙ ЖЕЛЕЗЫ

Высокодифференцированные формы рака щитовидной железы (ВДРЩЖ) составляют >90 % всех случаев рака щитовидной железы. У 10–15  % больных обнаруживаются отдаленные метастазы, что крайне ухудшает прогноз. Терапия радиоактивным йодом остается основным видом лечения для этой группы больных, но для пациентов с так называемым радиойодрефрактерным ВДРЩЖ прогноз крайне неблагоприятный. Несколько препаратов из группы мультикиназных ингибиторов после успешных исследований III фазы в настоящее время вошли в клиническую практику при лечении радиойодрефрактерного ВДРЩЖ, в частности ленватиниб. В своей работе мы представляем группу пациентов с радиойодрефрактерным ВДРЩЖ, которым проводилась терапия препаратом ленватиниб.

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