Method of maxillofacial reconstruction using individualized implants made of bioactive ceramics
https://doi.org/10.17650/2222-1468-2017-7-4-29-34
Abstract
Introduction. Many researchers are currently searching for new, safe, and effective methods of maxillofacial reconstruction in cancer patients.
In this case, special attention should be paid to ceramic implants.
Objective: to develop a personalized approach to the maxillofacial reconstruction using bioactive ceramic implants.
Materials and methods. We performed virtual planning of the implants for the reconstruction of the maxillofacial region basing on the preoperative spiral computed tomography scans of the facial skeleton.
Results. We have developed a new method of preoperative planning and creation of individualized implants made of bioactive ceramics for reconstructing the maxillofacial region. This method is demanded in reconstructive surgery and can be applied in routine clinical practice.
Conclusion. Reconstructive surgeries with the implants made of bioactive ceramics allow achieving good functional and aesthetic results in patients with large postoperative defects in the maxillofacial region, thus, improving their quality of life.
About the Authors
D. E. Kulbakin
Oncology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences;
National Research Tomsk State University, Ministry of Education and Science of Russia;
Tomsk State University of Control Systems and Radioelectronics;
Russian Federation
Russian Federation
Department of Head and Neck Tumors
5 Kooperativny lane, Tomsk, 634050, Russia;
36 Lenin Ave, Tomsk, 634050, Russia;
36 Lenin Ave, Tomsk, 634050, Russia;
E. L. Choynzonov
Oncology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences;
Tomsk State University of Control Systems and Radioelectronics;
Siberian State Medical University, Ministry of Health of Russia;
Russian Federation
Russian Federation
Department of Head and Neck Tumors
5 Kooperativny lane, Tomsk, 634050, Russia;
36 Lenin Ave, Tomsk, 634050, Russia;
2 Moskovskiy trakt, Tomsk, 634055, Russia
S. N. Kulkov
National Research Tomsk State University, Ministry of Education and Science of Russia;
Russian Federation
36 Lenin Ave, Tomsk, 634050, Russia;
Russian Federation
36 Lenin Ave, Tomsk, 634050, Russia;
S. P. Buyakova
National Research Tomsk State University, Ministry of Education and Science of Russia;
Russian Federation
36 Lenin Ave, Tomsk, 634050, Russia;
Russian Federation
36 Lenin Ave, Tomsk, 634050, Russia;
V. I. Chernov
Oncology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences;
Russian Federation
Russian Federation
Department of Head and Neck Tumors
5 Kooperativny lane, Tomsk, 634050, Russia;
M. R. Mukhamedov
Oncology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences;
Siberian State Medical University, Ministry of Health of Russia;
Russian Federation
Russian Federation
Department of Head and Neck Tumors
5 Kooperativny lane, Tomsk, 634050, Russia;
2 Moskovskiy trakt, Tomsk, 634055, Russia
A. S. Buyakov
National Research Tomsk State University, Ministry of Education and Science of Russia;
Russian Federation
36 Lenin Ave, Tomsk, 634050, Russia;
Russian Federation
36 Lenin Ave, Tomsk, 634050, Russia;
References
1. Состояние онкологической помощи населению России в 2016 году. Под ред. А. Д. Каприна, В. В. Старинского, Г. В. Петровой. М.: МНИОИ им. П. А. Герцена – филиал ФГБУ «НМИРЦ» Минздрава России, 2017. [The state of oncological care for the population of Russia in 2016. Eds.: A. D. Caprin, V. V. Starinsky, G. V. Petrova. Moscow: MNIOI imeni P. A. Hertzena – filial FGBU “NMIRC” Minzdrava Rossii, 2016. (In Russ.)].
2. Чойнзонов Е. Л., Новиков В. А., Мухамедов М. Р. и др. Комбинированное лечение злокачественных новообразований головы и шеи с реконструктивно-пластическими оперативными вмешательствами. Вопросы онкологии 2015;61(4):602–6. [Choynzonov E. L., Novikov V. A., Mukhamedov M. R. et al. Combined treatment of head and neck malignant tumors using reconstructive plastic surgery. Voprosy Onkologii = Oncology Issues 2015;61(4):602–6. (In Russ.)].
3. Jatin Shah’s Head and neck Surgery and Oncology. Eds.: J. P. Shah, S. G. Patel, B. Singh. Mosby, 2013. P. 713.
4. Neligan P. C. Head and Neck Reconstruction. Plast and Reconstr Surg 2013;131(2):260–9. DOI: 10.1097/ PRS.0b013e3182778938. PMID: 23358022.
5. Liu W. W., Peng H. W., Guo Z. M. et al. Immediate reconstruction of maxillectomy defects using anterolateral thigh free flap in patients from a low resource region. Laryngoscope 2012;122(11):2396–401. DOI: 10.1002/lary.23416. PMID: 22778002.
6. Bodhak S., Nath S., Basu B. Friction and wear properties of novel HDPE–Hap– Al2O3 biocomposites against alumina counterface. J Biomater Appl 2008;23(5):407–33. DOI: 10.1177/0885328208090012. PMID: 18667457.
7. Curran D. J., Fleming T. J., Towler M. R., Hampshire S. Mechanical properties of hydroxyapatite-zirconia compacts sintered by two different sintering methods. J Mater Sci Mater Med 2010;21(4):1109–20. DOI: 10.1007/ s10856-009-3974-z. PMID: 20037773.
8. Nair L. S., Laurencin С. Т. Biodegradable polymers as biomaterials. Prog Polym Sci 2007;32:762–98. DOI:10.1016/ j.progpolymsci.2007.05.017.
9. Redondo A., LeSar R. Modeling and simulation of biomaterials. Annu Rev Mater Res 2004;34:279–314. DOI: 10.1146/annurev. matsci.34.070503.12390.
10. Jégoux F., Goyenvalle E., Cognet R. et al. Franck Jegoux. Mandibular segmental defect regenerated with macroporous biphasic calcium phosphate, collagen membrane, and bone marrow graft in dogs. Arch Otolaryngol Head Neck Surg 2010;136(10):971–8. DOI:10.1001/ archoto.2010.173. PMID: 20956742.
11. Laurencin C. T., Khan Y., El-Amin S. F. Воnе graft substitutes. Expert Rev Med Devices 2006;3:49–57. DOI: 10.1586/17434440.3.1.49. PMID: 16359252.
12. Choynzonov E., Mukhamedov M., Kulbakin D. et al. Organ-preserving surgery using endografts from superelastic titanium-nickelid-based alloy for patients with laryngeal cancer. Adv Mater Res 2015;1085:414–8. DOI: 10.4028/www. scientific.net/AMR.1085.414.
13. Kulbakin D., Chekalkin T., Gunther V. et al. Sparing surgery for the successful treatment of thyroid papillary carcinoma invading the trachea: a case report. Case Rep Oncol 2016;9(3):772–80. DOI: 10.1159/000452790. PMID: 27990114.
14. Ginebra M. P., Traykova T., Planell J. A. Calcium phosphate cements as bone drug delivery systems: a review. J Control Release 2006;113:102–10. DOI: 10.1016/ j.jconrel.2006.04.007. PMID: 16740332.
15. Du B., Liu W., Deng Y. et al. Angiogenesis and bone regeneration of porous nanohydroxyapatite/coralline blocks coated with rhVEGF165 in critical-size alveolar bone defects in vivo. Int J Nanomedicine 2015;10:2555–65. DOI: 10.2147/IJN.S78331. PMCID: PMC4386782.
16. Shin U. S., Yoon I. K., Lee G. S. et al. Carbon nanotubes in nanocomposites and hybrids with hydroxyapatite for bone replacements. J Tissue Eng 2011;2011:674287. DOI: 10.4061/2011/674287. PMID: 21776341.
Review
For citations:
Kulbakin D.E., Choynzonov E.L., Kulkov S.N., Buyakova S.P., Chernov V.I., Mukhamedov M.R., Buyakov A.S. Method of maxillofacial reconstruction using individualized implants made of bioactive ceramics. Head and Neck Tumors (HNT). 2017;7(4):29-34. (In Russ.) https://doi.org/10.17650/2222-1468-2017-7-4-29-34
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