The necessity and advantages of personified neck lymph node dissection in T1-2N0M0 oral mucosa cancer. A pathway to radical surgery
G. Margolin,
A. М. Mudunov,
I. M. Gelfand,
Yu. V. Alymov,
A. A. Akhundov,
S. О. Podvyaznikov,
M. N. Narimanov,
T. N. Zabotina,
E. N. Zakharova https://doi.org/10.17650/2222-1468-2018-8-4-26-31
Abstract
The study objective is to investigate the causes of insufficient efficiency of neck lymph node dissection and possibilities of its improvement in cancer of the oral mucosa without clinically detectable metastases.
Materials and methods. A review of literature on surgical methods of affecting regional lymph collectors in cancers of the oral cavity was performed, and preliminary data on possibilities of biopsy of the sentinel lymph node were obtained.
Conclusion. Combination of fluorescent lymph node mapping andflow cytometry allows to identify the sentinel lymph node and detect hidden micrometastases with high sensitivity.
About the Authors
G. Margolin
Karolinska University Hospital, Karolinska Institute
Sweden
SE-171 77 Stockholm
Sweden
SE-171 77 Stockholm
A. М. Mudunov
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
24 Kashirskoe Shosse, Moscow 115478
I. M. Gelfand
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
24 Kashirskoe Shosse, Moscow 115478
Yu. V. Alymov
Russian Medical Academy of Continuing Professional Education, Ministry of Health of Russia
Russian Federation
Russian Federation
Build. 1, 2/1 Barrikadnaya St., Moscow 125993
A. A. Akhundov
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
24 Kashirskoe Shosse, Moscow 115478
S. О. Podvyaznikov
Russian Medical Academy of Continuing Professional Education, Ministry of Health of Russia
Russian Federation
Russian Federation
Build. 1, 2/1 Barrikadnaya St., Moscow 125993
M. N. Narimanov
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
24 Kashirskoe Shosse, Moscow 115478
T. N. Zabotina
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
24 Kashirskoe Shosse, Moscow 115478
E. N. Zakharova
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
Russian Federation
Russian Federation
24 Kashirskoe Shosse, Moscow 115478
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Review
For citations:
Margolin G., Mudunov A.М., Gelfand I.M., Alymov Yu.V., Akhundov A.A., Podvyaznikov S.О., Narimanov M.N., Zabotina T.N., Zakharova E.N. The necessity and advantages of personified neck lymph node dissection in T1-2N0M0 oral mucosa cancer. A pathway to radical surgery. Head and Neck Tumors (HNT). 2018;8(4):26-31. (In Russ.) https://doi.org/10.17650/2222-1468-2018-8-4-26-31
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