Combination of Forestier’s disease and laryngeal cancer: a rare clinical case
А. М. Zaytsev,
А. P. Polyakov,
М. V. Ratushny,
Т. М. Kobyletskaya,
S. А. Kisariev,
А. L. Sugaipov,
О. N. Kirsanova https://doi.org/10.17650/2222-1468-2020-10-2-79-84
Abstract
The objective of the scientific report is to describe a rare clinical case of a combination of Forestier’s disease (diffuse idiopathic skeletal hyperostosis) and laryngeal cancer that have common symptoms.
Case report. A 68-year-old male patient presented with hoarseness lasting for a year. Indirect laryngoscopy revealed a vocal fold tumor. Histological examination confirmed well-differentiated keratinizing squamous cell carcinoma of the larynx. A 6-cm tumor was located in the projection of the right vocal fold and had no signs of invasion into the supraglottis, subglottis, and anterior commissure. No other focal disorders were detected. The patient has undergone endolaryngeal laser resection of the larynx and tracheostomy. After probe removal, the patient had swallowing difficulties with esophageal content passing to the trachea mainly due to organic changes in the cervical spine at the СЗ–С4 level, where there was a massive local calcification of the anterior longitudinal ligament. We also noticed severe movement restriction in the cervical spine: the amplitude of movements did not exceed 10°. The formation of the C3–C4 segment was removed via ventrolateral approach.
Conclusion. Dysphagia, dysphonia, and dyspnea may indicate both malignant tumor and large osteophyte causing compression of the trachea and esophagus. In this case, no symptom resolution after tumor removal led to the suspicion of a second disease, namely Forestier’s
disease.
About the Authors
А. М. Zaytsev
P.A. Hertzen Moscow Oncology Research Institute – branch of the National Medical Research Radiology Center, Ministry of Health of Russia
Russian Federation
3 2nd Botkinsky Dr., Moscow 125284
Russian Federation
3 2nd Botkinsky Dr., Moscow 125284
А. P. Polyakov
P.A. Hertzen Moscow Oncology Research Institute – branch of the National Medical Research Radiology Center, Ministry of Health of Russia
Russian Federation
3 2nd Botkinsky Dr., Moscow 125284
Russian Federation
3 2nd Botkinsky Dr., Moscow 125284
М. V. Ratushny
P.A. Hertzen Moscow Oncology Research Institute – branch of the National Medical Research Radiology Center, Ministry of Health of Russia
Russian Federation
3 2nd Botkinsky Dr., Moscow 125284
Russian Federation
3 2nd Botkinsky Dr., Moscow 125284
Т. М. Kobyletskaya
P.A. Hertzen Moscow Oncology Research Institute – branch of the National Medical Research Radiology Center, Ministry of Health of Russia
Russian Federation
3 2nd Botkinsky Dr., Moscow 125284
Russian Federation
3 2nd Botkinsky Dr., Moscow 125284
S. А. Kisariev
P.A. Hertzen Moscow Oncology Research Institute – branch of the National Medical Research Radiology Center, Ministry of Health of Russia
Russian Federation
3 2nd Botkinsky Dr., Moscow 125284
Russian Federation
3 2nd Botkinsky Dr., Moscow 125284
А. L. Sugaipov
P.A. Hertzen Moscow Oncology Research Institute – branch of the National Medical Research Radiology Center, Ministry of Health of Russia
Russian Federation
3 2nd Botkinsky Dr., Moscow 125284
Russian Federation
3 2nd Botkinsky Dr., Moscow 125284
О. N. Kirsanova
P.A. Hertzen Moscow Oncology Research Institute – branch of the National Medical Research Radiology Center, Ministry of Health of Russia
Russian Federation
3 2nd Botkinsky Dr., Moscow 125284
Russian Federation
3 2nd Botkinsky Dr., Moscow 125284
References
1. Злокачественные новообразования в России в 2018 году (заболеваемость и смертность). Под ред. А.Д. Каприна, В.В. Старинского, Г.В. Петровой. М.: МНИОИ им. П.А. Герцена, 2019. 250 с. Доступно по: http://www.glavonco.ru/cancer_register/Забол_2018_Электр.pdf. [Malignant tumors in Russia in 2018 (morbidity and mortality). Ed by A.D. Kaprin, V.V. Starinsky, G.V. Petrova. Moscow: MNIOI im. P.A. Gertzena, 2019. 250 p. Available at: http://www.glavonco.ru/cancer_register/Забол_2018_Электр. pdf. (In Russ.)].
2. Kuper H., Boffetta P., Adami H.O. Tobacco use and cancer causation: association by tumour type. J Intern Med 2002;252(3):206–24. DOI: 10.1046/j.1365-2796.2002.01022.x.
3. Holton K.F., Denard P.J., Yoo J.U. et al. Diffuse idiopathic skeletal hyperostosis and its relation to back pain among older men: the MrOS Study. Semin Arthritis Rheum 2011;41(2):131–8. DOI: 10.1016/j.semarthrit.2011.01.001.
4. Forestier J., Rotes-Querol J. Senile ankylosing hyperostosis of the spine. Ann Rheum Dis 1950;9(4):321–30. DOI: 10.1136/ard.9.4.321.
5. Resnick D., Niwayama G. Radiographic and pathologic features of spinal involvement in diffuse idiopathic skeletal hyperostosis (DISH). Radiology 1976;119(3):559–68. DOI: 10.1148/119.3.559.
6. Pulcherio J.O., Velasco C.M., Machado R.S. et al. Forestier’s disease and its implications in otolaryngology: literature review. Braz J Otorhinolaryngol 2014;80(2):161–6. DOI: 10.5935/1808-8694.20140033.
7. Miyamoto K., Sugiyama S., Hosoe H. et al. Postsurgical recurrence of osteophytes causing dysphagia in patients with diffuse idiopathic skeletal hyperostosis. Eur Spine J 2009;18(11):1652–8. DOI: 10.1007/s00586-009-1133-3.
8. Гончаров М.Ю., Прокопович В.С. Болезнь Форестье как причина вторичной дисфагии в неврологической практике. Уральский медицинский журнал 2017;(10):19–21. [Goncharov M.Yu., Prokopovich V.S. Forestier’s disease as the cause of secondary dysphagia in neurological practice. Uralsky meditsinsky zhurnal = Ural Medical Journal 2017;(10):19–21. (In Russ.)].
Review
For citations:
Zaytsev А.М., Polyakov А.P., Ratushny М.V., Kobyletskaya Т.М., Kisariev S.А., Sugaipov А.L., Kirsanova О.N. Combination of Forestier’s disease and laryngeal cancer: a rare clinical case. Head and Neck Tumors (HNT). 2020;10(2):79-84. (In Russ.) https://doi.org/10.17650/2222-1468-2020-10-2-79-84
Views:
887
Email this article 