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BRAIN METASTASIS FROM HEPATOCELLULAR CARCINOMA: A RARE CASE

https://doi.org/10.17650/2222-1468-2012-0-3-73-79

Abstract

Hepatocellular carcinoma ranks 5th in prevalence and 3rd in cancer mortality worldwide. The prognosis of this disease is very poor: the 5-year survival rate was not more than 3–5%. Metastases generally occur in the lung, in the lymph nodes of the abdomen, chest, and neck, in the vertebrae, kidneys, and adrenals. The cases of brain metastasis from hepatocellular cancer are very rare. Overall, the prognosis is very poor for patients with brain metastases from hepatocellular carcinoma. Nevertheless, solitary brain metastases and good hepatic function are favorable survival criteria; thus, the treatment of this group of patients may lead to their better survival. The paper describes a clinical case of brain metastasis from hepatocellular carcinoma in a patient receiving the combination treatment involving neurosurgical treatment and targeted therapy. 

About the Authors

A. Kh. Bekyashev
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow; Russian Medical Academy of Postgraduate Education, Ministry of Health of Russia, Moscow
Russian Federation
Department of Neurosurgery


N. V. Sevyan
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow
Russian Federation


D. M. Belov
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow
Russian Federation


A. V. Zotov
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow
Russian Federation


Yu. V. Tsybulskaya
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow
Russian Federation


D. R. Naskhletashvili
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow
Russian Federation


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For citations:


Bekyashev A.Kh., Sevyan N.V., Belov D.M., Zotov A.V., Tsybulskaya Yu.V., Naskhletashvili D.R. BRAIN METASTASIS FROM HEPATOCELLULAR CARCINOMA: A RARE CASE. Head and Neck Tumors (HNT). 2012;(3):73-79. (In Russ.) https://doi.org/10.17650/2222-1468-2012-0-3-73-79

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ISSN 2222-1468 (Print)
ISSN 2411-4634 (Online)