Vol 6, No 3 (2016)

Administration of calcium and vitamin D preparations always requires competent selection of doses, and combinations of drugs from a doctor as well as careful clinical and laboratory monitoring of the patient. Physician should always be aware of the danger of overdose, which can lead to very adverse consequences. An appearance of the first symptoms of overdose requires constant laboratory control and urgent measures to address this condition. One should also remember about other causes of hypercalcemia, which can help in the differential diagnosis. Clinical case presented by us is an example of how the lack of knowledge about the combined treatment of patients with postsurgical hypoparathyroidism can lead to some serious consequences such as hypercalcemic crisis. 

The work illustrates main issues of the radial treatment acceptability with the modification of patients with the squamous cell carcinoma of the oropharyngeal area. The spectrum of side effects is given and key issues of the accompanying therapy are concerned. Separately are given approaches to the treatment of patients with radial mucositis and dermatitis. 

In the treatment of many unresolved issues, indicating the need for research aimed at finding more effective treatment approaches. The aim of the study is to analyze the results of combined treatment of patients with widespread forms of cancer of the cervical esophagus and hypopharynx with the application of surgical treatment in the amount of pharyngolaryngitis with single-step plastic of the defect. A retrospective analysis of results of combined treatment of 28 patients with a verified diagnosis of cancer of the cervical esophagus and hypopharynx. Combined treatment of patients with cancer of the cervical esophagus and hypopharynx included the following treatments: induction chemoradiotherapy according to the scheme cisplatin/5-fluorouracil, external beam radiation therapy 65 Gy, brachytherapy (7 Gy 1 time per week, 3 sessions), surgical treatment with one-stage plastic of the esophagus. In 7 patients (25 %) was achieved complete regression on the background of induction chemo-therapy, 21 patients (75 %) received the treatment in full. Postoperative mortality rate was of 9.52 %, post-operative complications such as anastomosis dehiscence – 19 %.